Cell assemblies in the neocortex
Erik Fransen
Dept. of Numerical Analysis and Computer Science,
Royal Institute of Technology,
S-100 44 Stockholm,
Sweden
Abstract:
The cell assembly is a conceptual entity introduced by D. O. Hebb in
his classic book The organization of behavior. Within this book, Hebb
described how the cell assembly would be formed, and how it could support
internal representations of entities in the surrounding world. He also
discussed associations between assemblies and sequences of such, as
elements of "thought". The hypothesis has been adopted and extended by many.
We have studied how this qualitative hypothesis could be formulated in a
quantitative computational framework. We have also investigated its support
from modern neuroscience in terms of structure and function. In a
biophysical model, we have tested the performance for the assembly
functions, as well as other computational variables such as speed of
recall, unit activity levels, and flexibility of operation. In the
presentation, the possibility that assembly-like operations may be
present in multiple regions of the cortex, including its relations
to the long-term and working memory function attributed to these regions,
will also be discussed.