Optimization and Simulation in Drug Development - Review and Analysis



AbstractWe give a review of pharmaceutical R&D and mathematical simulation and optimization methods used to support decision making within the pharmaceutical development process.

The complex nature of drug development is pointed out through a description of the various phases of the pharmaceutical development process. A part of the paper is dedicated to the use of simulation techniques to support clinical trials. The paper ends with a section describing portfolio modelling methods in the context of the pharmaceutical industry.
KeywordsPharmaceutical R&D, Drug Discovery and Development, Modelling and simulation, Clinical Trial Simulation Portfolio optimization
TypeTechnical report
Year2003
PublisherInformatics and Mathematical Modelling, Technical University of Denmark, DTU
AddressRichard Petersens Plads, Building 321, DK-2800 Kgs. Lyngby
SeriesIMM-Technical report-2003-26
Electronic version(s)[ps]
BibTeX data [bibtex]
IMM Group(s)Operations Research